This systematic review examines the long-term patient-reported outcomes related to mental health, sexual, and urinary function in patients on active surveillance (AS) for low-risk prostate cancer.
The analysis includes 19 studies involving 3,643 AS patients, 14,651 patients who underwent surgery or radiotherapy, and 2,478 controls without prostate cancer. The findings indicate that patients on AS experience better sexual function and fewer urinary symptoms compared to those who received interventional treatments.
Overall, the health-related quality of life for AS patients was comparable to that of individuals without prostate cancer, supporting AS as a recommended management strategy for appropriately selected patients.